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Bioactive constituents of Spatholobus suberectus in regulating tyrosinase-related proteins and mRNA in HEMn cells – ScienceDirect
1/6/2006 · Cells (1 × 10 6) were lysed with PBS containing 1% TritonX-100, 1 mM phenylmethylsulfonyl fluoride (PMSF), 1 mg/ml aprotinin, and 10 mg/ml leupeptin, and lysates were subjected to centrifugation at 12,000g for 10 min. The total protein content
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In one report (37) on the safety of jixueteng injection (with Spatholobus suberectus specified as the source material), it was stated that its tolerance dose in mice was 200 times the therapeutic dose and that the LD 50 in mice was over 100 g/kg
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11/12/2019 · Background An extract from Spatholobus suberectus (S. suberectus) Dunn has been reported to show potent antimutagenic effects against N-alkyl-N-nitrosoureas in umu screening. The aim of this study was to identify the antimutagenic components
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Antimutagenic components in Spatholobus suberectus Dunn against N-methyl-N-nitrosourea | Genes and Environment | Full Text
11/12/2019 · Background An extract from Spatholobus suberectus (S. suberectus) Dunn has been reported to show potent antimutagenic effects against N-alkyl-N-nitrosoureas in umu screening. The aim of this study was to identify the antimutagenic components
Flavonoids from Spatholobus suberectus | Request PDF
Compounds 1 and 2 exhibited antioxidant activities in 2,2-diphenyl-1-(2,4,6-trinitrophenyl)hydrazyl free radical scavenging assays, with IC50 values of 35.9 ± 1.1 and 12.2 ± 1.1 µM
Antimutagenic components in Spatholobus suberectus Dunn against N-methyl-N-nitrosourea – ResearchGate
Background: An extract from Spatholobus suberectus (S. suberectus) Dunn has been reported to show potent antimutagenic effects against N-alkyl-N-nitrosoureas in umu screening. The aim of this
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Molecules | Free Full-Text | In Vitro Study on Anti-Hepatitis C Virus Activity of Spatholobus suberectus Dunn | HTML
The EC 50 of S. suberectus extracts, except the aqueous extract (JXT-E0; Table 2) against HCV was approximately 1 μg/mL. Moreover, 100 μg/mL S. suberectus extract did not elicit cytotoxic effects except the aqueous extract of JXT-E0 (). S. suber
UPLC–MS/MS assay for simultaneous determination of four compounds in rat plasma: application to pharmacokinetic study after oral administration
1/11/2016 · The four components were separated on an Agilent Zorbax Eclipse Plus C18 column (2.1 × 50 mm, 1.8 μm) with the mobile phase consisting of water containing 0.05% formic acid and methanol (35:65, v/v), and detected by negative ion electrospray
Ultrasonic/microwave assisted extraction and diagnostic ion filtering strategy by liquid chromatography–quadrupole time-of-flight mass
26/8/2011 · Sixty mesh powder of 1.0 g was extracted with 80 mL 100% methanol using soxhlet apparatus for 6 h under a temperature of 80 C. The extract was then concentrated using rotary vacuum evaporator. 2.2.5. Heat reflux extraction (HRE) HRE was conducte
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In Vitro Study on Anti-Hepatitis C Virus Activity of Spatholobus suberectus Dunn. – Abstract – Europe PMC
15/10/2016 · S. suberectus extracts, especially 50% ethanol-eluted fraction (JXT-E50), was the most potent (Table 1 and Table 2, and Figure 2, Figure 3 and Figure 4). Aqueous and methanolic S. suberectus extracts inhibit the production of Dactylogyrus
The optimization of ultrasonic-microwave assisted synergistic extraction of Lotus plumule extract rich in flavonoids and its hypoglycemic activity
29/7/2021 · Ten mice were assigned to feed normal diet, the other 50 mice were fed high-fat high-sucrose diet (HFHS, 63.6% basic forage, 15% sucrose, 10% egg yolk powder, 10% lard, 1.2% cholesterol, and 0.2% sodium cholate).
PhytochemicalCharacteristics,FreeRadicalScavenging Activities,andNeuroprotectionofFiveMedicinalPlantExtracts – Hindawi
and neuroprotective effects [10]. Thus, we also investigated induced neurogrowth and neuroprotective effects on H 2O 2-induced PC12 cell death of the five plant extracts. 2.MaterialsandMethods 2.1. Materials. The dried vine stems of S. suberectus,
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1. Introduction
Aqueous extract of JXT markedly dampens the mRNA expression of CVB3 and severally reduces 15-day mortality to forty percent and forty-five percent and 30-day mortality to forty-five percent and fifty percent at doses of 50 mg/kg and 100 mg/kg in
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